If you’re applying for residency, one tool that can help you stand out is a Letter of Interest (LOI). This short, formal document allows you to communicate your enthusiasm for a program, highlight your most relevant experiences, and show program directors why you’d be an excellent fit.
In this guide, we’ll cover what a residency LOI is, why it matters, when to send it, what to include, and common mistakes to avoid.
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A residency letter of interest is a professional letter sent to program directors expressing your desire to join their program. It goes beyond what’s already on your ERAS application by giving you space to:
While a letter of intent usually carries a strong commitment (such as promising to attend if accepted), a letter of interest is less binding—it’s meant to signal genuine enthusiasm and keep you top-of-mind with program staff.
Writing an LOI can help you in several ways:
Shows that you’ve done your research and are truly motivated to join that program.
A chance to share recent achievements, research, or honors not included in your original application.
Opens a line of communication with faculty and directors.
Particularly useful if you haven’t been invited to interview yet or are on a waitlist.
The best time to send a letter of interest is after submitting your application and/or after your interview. Sending it later in the process helps reinforce your interest and ensures the program is aware of your continued commitment.
Keep your letter concise (200–300 words, one page maximum) and professional. A solid structure includes:
Reference unique aspects of the program that resonate with you (faculty, research focus, patient population, etc.).
Use formal language and avoid slang or casual expressions.
Never send a generic letter to multiple programs.
Errors can make your letter less persuasive.
Focus on fit, not on comparisons or complaints about other programs.
[Your Name]
[Your Address]
[Program Director’s Name, Title]
[Residency Program Name]
[Program Address]
[City, State, ZIP Code]
Dear Dr. XYZ,
I am writing to express my strong interest in the [Residency Program Name] [Specialty] residency program. After learning more about your program through [specific detail: interview, rotation, open house, etc.], I am excited about the opportunity to train at [Residency Program Name].
My experiences in [specific clinical/research experience] have prepared me to thrive in a program with a strong focus on [specific program features]. I was particularly impressed by [mention something distinctive about the program patient population, curriculum, mentorship, etc.], which aligns closely with my career goals of becoming a [specialty] physician committed to [career focus, e.g., academic medicine, underserved care, research].
I believe my background in [relevant experience] and dedication to [specialty] will allow me to contribute meaningfully to your residency community. Thank you for your time and consideration, and I look forward to the opportunity to continue growing within [Residency Program Name].
Sincerely,
[Your Full Name]
AAMC ID
A letter of interest is a simple but powerful way to show residency programs that you’re motivated, prepared, and committed to joining their community. Keep it clear, professional, and personalized and you’ll increase your chances of standing out in a competitive match cycle.
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Recent Articles , Medical Electives, Residency,
Author: Go-Elective Abroad
Date Published: Dec 15, 2025
Go Elective offers immersive opportunities for medical students, pre-med undergraduates, residents, nursing practitioners, and PAs to gain guided invaluable experience in busy hospitals abroad. Discover the power of study, travel, and impact.